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Identification of specific let-7 microRNA binding complexes in Caenorhabditis elegans

Little is known about the protein complexes required for microRNA formation and function. Here we used native gel electrophoresis to identify miRNA ribonucleoprotein complexes (miRNPs) in Caenorhabditis elegans. Our data reveal multiple distinct miRNPs that assemble on the let-7 miRNA in vitro. The...

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Detalhes bibliográficos
Main Authors: Chan, Shih-Peng, Ramaswamy, Gopalakrishna, Choi, Eun-Young, Slack, Frank J.
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2553747/
https://ncbi.nlm.nih.gov/pubmed/18719242
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.551208
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