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Splicing remodels the let-7 primary microRNA to facilitate Drosha processing in Caenorhabditis elegans

MicroRNAs (miRNAs) are a class of small noncoding RNAs that use partial base-pairing to recognize and regulate the expression of messenger RNAs (mRNAs). Mature miRNAs arise from longer primary transcripts (pri-miRNAs) that are processed to a shorter hairpin precursor miRNA (pre-miRNA) by the Micropr...

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Détails bibliographiques
Publié dans:RNA
Auteurs principaux: Mondol, Vanessa, Ahn, Byoung Chan, Pasquinelli, Amy E.
Format: Artigo
Langue:Inglês
Publié: Cold Spring Harbor Laboratory Press 2015
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4509930/
https://ncbi.nlm.nih.gov/pubmed/26081559
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.052118.115
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