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Trans-splicing and polyadenylation of let-7 microRNA primary transcripts

Members of the microRNA (miRNA) class of 22-nucleotide RNAs regulate the expression of target genes that contain sequences of antisense complementarity. Maturation of miRNAs involves cleavage of longer primary transcripts, but little is yet understood about how miRNA genes are transcribed and enter...

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Main Authors: BRACHT, JOHN, HUNTER, SHAUN, EACHUS, RACHEL, WEEKS, PHILLIP, PASQUINELLI, AMY E.
Format: Artigo
Jezik:Inglês
Izdano: Copyright 2004 by RNA Society 2004
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC1370645/
https://ncbi.nlm.nih.gov/pubmed/15337850
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.7122604
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