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Repression of C. elegans microRNA targets at the initiation level of translation requires GW182 proteins
MicroRNAs (miRNAs) repress target genes through a poorly defined antisense mechanism. Cell-free and cell-based assays have supported the idea that miRNAs repress their target mRNAs by blocking initiation of translation, whereas studies in animal models argued against this possibility. We examined en...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2637332/ https://ncbi.nlm.nih.gov/pubmed/19131968 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2008.275 |
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