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A role for the P-body component, GW182, in microRNA function

In animals, the majority of microRNAs regulate gene expression through the RNAi machinery without inducing small RNA-directed mRNA cleavage 1. Thus, the mechanisms by which microRNAs repress their targets have remained elusive. Recently, Argonaute proteins, which are key RNAi effector components, an...

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Detalhes bibliográficos
Main Authors: Liu, Jidong, Rivas, Fabiola V., Wohlschlegel, James, Yates, John R., Parker, Roy, Hannon, Gregory J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2005
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1804202/
https://ncbi.nlm.nih.gov/pubmed/16284623
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncb1333
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