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The GW/WG repeats of Drosophila GW182 function as effector motifs for miRNA-mediated repression
The control of messenger RNA (mRNA) function by micro RNAs (miRNAs) in animal cells requires the GW182 protein. GW182 is recruited to the miRNA repression complex via interaction with Argonaute protein, and functions downstream to repress protein synthesis. Interaction with Argonaute is mediated by...
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| Main Authors: | , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Oxford University Press
2010
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2965232/ https://ncbi.nlm.nih.gov/pubmed/20530530 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkq501 |
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