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Importance of the C-terminal domain of the human GW182 protein TNRC6C for translational repression

Proteins of the GW182 family play an important role in the execution of microRNA repression in metazoa. They interact directly with Argonaute proteins, components of microRNPs, and also form part of P-bodies, structures implicated in translational repression and mRNA degradation. Recent results demo...

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Main Authors: Zipprich, Jakob T., Bhattacharyya, Sankar, Mathys, Hansruedi, Filipowicz, Witold
Formáid: Artigo
Teanga:Inglês
Foilsithe: Cold Spring Harbor Laboratory Press 2009
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2673060/
https://ncbi.nlm.nih.gov/pubmed/19304925
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.1448009
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