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The GW/WG repeats of Drosophila GW182 function as effector motifs for miRNA-mediated repression

The control of messenger RNA (mRNA) function by micro RNAs (miRNAs) in animal cells requires the GW182 protein. GW182 is recruited to the miRNA repression complex via interaction with Argonaute protein, and functions downstream to repress protein synthesis. Interaction with Argonaute is mediated by...

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Hlavní autoři: Chekulaeva, Marina, Parker, Roy, Filipowicz, Witold
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2010
Témata:
RNA
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2965232/
https://ncbi.nlm.nih.gov/pubmed/20530530
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkq501
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