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Conformational changes in α7 acetylcholine receptors underlying allosteric modulation by divalent cations

Allosteric modulation of membrane receptors is a widespread mechanism by which endogenous and exogenous agents regulate receptor function. For example, several members of the nicotinic receptor family are modulated by physiological concentrations of extracellular calcium ions. In this paper, we exam...

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Autors principals: McLaughlin, James T, Barron, Sean C, See, Jennifer A, Rosenberg, Robert L
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2009
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2632993/
https://ncbi.nlm.nih.gov/pubmed/19144123
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2210-9-1
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