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Conformational changes in α7 acetylcholine receptors underlying allosteric modulation by divalent cations

Allosteric modulation of membrane receptors is a widespread mechanism by which endogenous and exogenous agents regulate receptor function. For example, several members of the nicotinic receptor family are modulated by physiological concentrations of extracellular calcium ions. In this paper, we exam...

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Detalhes bibliográficos
Main Authors: McLaughlin, James T, Barron, Sean C, See, Jennifer A, Rosenberg, Robert L
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2632993/
https://ncbi.nlm.nih.gov/pubmed/19144123
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2210-9-1
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