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Thiamin Biosynthesis in Eukaryotes: Characterization of the Enzyme Bound Product of Thiazole Synthase from Saccharomyces cerevisiae and Its Implications in Thiazole Biosynthesis

The biosynthesis of thiamin pyrophosphate in eukaryotes is different from the prokaryotic biosynthesis and is poorly understood to date. Only one thiazole biosynthetic gene has been identified (Thi4 in Saccharomyces cerevisiae). Here we report the identification and characterization of a Thi4 bound...

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Autors principals: Chatterjee, Abhishek, Jurgenson, Christopher T., Schroeder, Frank C., Ealick, Steven E., Begley, Tadhg P.
Format: Artigo
Idioma:Inglês
Publicat: 2006
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2631426/
https://ncbi.nlm.nih.gov/pubmed/16734458
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja061413o
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