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Lymphocyte-Specific Compensation For XLF/Cernunnos End-Joining Functions In V(D)J Recombination
Mutations in XLF/Cernunnos (hereafter called "XLF") cause lymphocytopenia in humans, and various studies suggest an XLF role in classical non-homologous end joining (C-NHEJ). We now find that XLF-deficient mouse embryonic fibroblasts are ionizing radiation (IR) sensitive and severely impai...
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| 主要な著者: | , , , , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2008
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2630261/ https://ncbi.nlm.nih.gov/pubmed/18775323 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2008.07.017 |
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