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Positive selection on the nonhomologous end-joining factor Cernunnos-XLF in the human lineage

BACKGROUND: Cernunnos-XLF is a nonhomologous end-joining factor that is mutated in patients with a rare immunodeficiency with microcephaly. Several other microcephaly-associated genes such as ASPM and microcephalin experienced recent adaptive evolution apparently linked to brain size expansion in hu...

詳細記述

保存先:
書誌詳細
主要な著者: Pavlicek, Adam, Jurka, Jerzy
フォーマット: Artigo
言語:Inglês
出版事項: BioMed Central 2006
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC1552050/
https://ncbi.nlm.nih.gov/pubmed/16749933
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1745-6150-1-15
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