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XLF/Cernunnos: An important but puzzling participant in the nonhomologous end joining DNA repair pathway

DNA double strand breaks (DSBs) are one of the most deleterious DNA lesions that promote cell death, genomic instability and carcinogenesis. The two major cellular mechanisms that repair DSBs are Nonhomologous End-Joining (NHEJ) and Homologous Recombination Repair (HRR). NHEJ is the predominant path...

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書誌詳細
出版年:DNA Repair (Amst)
主要な著者: Menon, Vijay, Povirk, Lawrence F.
フォーマット: Artigo
言語:Inglês
出版事項: 2017
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC6685063/
https://ncbi.nlm.nih.gov/pubmed/28846869
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.dnarep.2017.08.003
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