Cargando...

Involvement of p53 in the repair of DNA double strand breaks: Multifaceted roles of p53 in homologous recombination repair (HRR) and non-homologous end joining (NHEJ)

p53 is a tumor suppressor protein that prevents oncogenic transformation and maintains genomic stability by blocking proliferation of cells harboring unrepaired or misrepaired DNA. A wide range of genotoxic stresses such as DNA damaging anti-cancer drugs and ionizing radiation promote nuclear accumu...

Descrición completa

Gardado en:
Detalles Bibliográficos
Publicado en:Subcell Biochem
Main Authors: Menon, Vijay, Povirk, Lawrence
Formato: Artigo
Idioma:Inglês
Publicado: 2014
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4235614/
https://ncbi.nlm.nih.gov/pubmed/25201202
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/978-94-017-9211-0_17
Tags: Engadir etiqueta
Sen Etiquetas, Sexa o primeiro en etiquetar este rexistro!