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Positive selection on the nonhomologous end-joining factor Cernunnos-XLF in the human lineage
BACKGROUND: Cernunnos-XLF is a nonhomologous end-joining factor that is mutated in patients with a rare immunodeficiency with microcephaly. Several other microcephaly-associated genes such as ASPM and microcephalin experienced recent adaptive evolution apparently linked to brain size expansion in hu...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
BioMed Central
2006
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| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1552050/ https://ncbi.nlm.nih.gov/pubmed/16749933 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1745-6150-1-15 |
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