A Decrease in Anandamide Signaling Contributes to the Maintenance of Cutaneous Mechanical Hyperalgesia in a Model of Bone Cancer Pain

Tumors in bone are associated with pain in humans. Data generated in a murine model of bone cancer pain suggest that a disturbance of local endocannabinoid signaling contributes to the pain. When tumors formed after injection of osteolytic fibrosarcoma cells into the calcaneus bone of mice, cutaneou...

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Autori principali: Khasabova, Iryna A., Khasabov, Sergey G., Harding-Rose, Catherine, Coicou, Lia G., Seybold, Bryan A., Lindberg, Amy E., Steevens, Christopher D., Simone, Donald A., Seybold, Virginia S.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Society for Neuroscience 2008
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Articles
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2628759/
https://ncbi.nlm.nih.gov/pubmed/18971457
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.2847-08.2008
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