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Cannabinoid Type-1 Receptor Reduces Pain and Neurotoxicity Produced by Chemotherapy

Painful peripheral neuropathy is a dose-limiting complication of chemotherapy. Cisplatin produces a cumulative toxic effect on peripheral nerves, and 30–40% of cancer patients receiving this agent experience pain. By modeling cisplatin-induced hyperalgesia in mice with daily injections of cisplatin...

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Detalhes bibliográficos
Main Authors: Khasabova, Iryna A., Khasabov, Sergey, Paz, Justin, Harding-Rose, Catherine, Simone, Donald A., Seybold, Virginia S.
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3366638/
https://ncbi.nlm.nih.gov/pubmed/22593077
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.0403-12.2012
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