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Increasing 2-arachidonoyl glycerol signaling in the periphery attenuates mechanical hyperalgesia in a model of bone cancer pain

Metastatic and primary bone cancers are usually accompanied by severe pain that is difficult to manage. In light of the adverse side effects of opioids, manipulation of the endocannabinoid system may provide an effective alternative for the treatment of cancer pain. The present study determined that...

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Autors principals: Khasabova, Iryna A., Chandiramani, Anisha, Harding-Rose, Catherine, Simone, Donald A., Seybold, Virginia S.
Format: Artigo
Idioma:Inglês
Publicat: 2011
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3104059/
https://ncbi.nlm.nih.gov/pubmed/21440630
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.phrs.2011.03.007
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