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Sensitization of nociceptors by prostaglandin E(2)–glycerol contributes to hyperalgesia in mice with sickle cell disease
Pain is a characteristic feature of sickle cell disease (SCD), 1 of the most common inherited diseases. Patients may experience acute painful crises as well as chronic pain. In the Berkley transgenic murine model of SCD, HbSS-BERK mice express only human hemoglobin S. These mice share many features...
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| Publicado no: | Blood |
|---|---|
| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society of Hematology
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6497514/ https://ncbi.nlm.nih.gov/pubmed/30796025 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2018-11-884346 |
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