Pain-related behaviors and neurochemical alterations in mice expressing sickle hemoglobin: modulation by cannabinoids

Sickle cell disease causes severe pain. We examined pain-related behaviors, correlative neurochemical changes, and analgesic effects of morphine and cannabinoids in transgenic mice expressing human sickle hemoglobin (HbS). Paw withdrawal threshold and withdrawal latency (to mechanical and thermal st...

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Autores principales: Kohli, Divyanshoo R., Li, Yunfang, Khasabov, Sergey G., Gupta, Pankaj, Kehl, Lois J., Ericson, Marna E., Nguyen, Julia, Gupta, Vinita, Hebbel, Robert P., Simone, Donald A., Gupta, Kalpna
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society of Hematology 2010
Materias:
Red Cells, Iron, and Erythropoiesis
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2913454/
https://ncbi.nlm.nih.gov/pubmed/20304807
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2010-01-260372
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