Pain-related behaviors and neurochemical alterations in mice expressing sickle hemoglobin: modulation by cannabinoids

Sickle cell disease causes severe pain. We examined pain-related behaviors, correlative neurochemical changes, and analgesic effects of morphine and cannabinoids in transgenic mice expressing human sickle hemoglobin (HbS). Paw withdrawal threshold and withdrawal latency (to mechanical and thermal st...

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Bibliografiska uppgifter
Huvudupphovsmän: Kohli, Divyanshoo R., Li, Yunfang, Khasabov, Sergey G., Gupta, Pankaj, Kehl, Lois J., Ericson, Marna E., Nguyen, Julia, Gupta, Vinita, Hebbel, Robert P., Simone, Donald A., Gupta, Kalpna
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Society of Hematology 2010
Ämnen:
Red Cells, Iron, and Erythropoiesis
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC2913454/
https://ncbi.nlm.nih.gov/pubmed/20304807
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2010-01-260372
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