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Aag-initiated base excision repair drives alkylation-induced retinal degeneration in mice
Vision loss affects >3 million Americans and many more people worldwide. Although predisposing genes have been identified their link to known environmental factors is unclear. In wild-type animals DNA alkylating agents induce photoreceptor apoptosis and severe retinal degeneration. Alkylation-ind...
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| Autors principals: | , , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
National Academy of Sciences
2009
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2621254/ https://ncbi.nlm.nih.gov/pubmed/19139400 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0807030106 |
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