Genetic Variation on Chromosome 6 Influences F Cell Levels in Healthy Individuals of African Descent and HbF Levels in Sickle Cell Patients

Fetal haemoglobin (HbF) is a major ameliorating factor in sickle cell disease. We investigated if a quantitative trait locus on chromosome 6q23 was significantly associated with HbF and F cell levels in individuals of African descent. Single nucleotide polymorphisms (SNPs) in a 24-kb intergenic regi...

Полное описание

Сохранить в:
Библиографические подробности
Главные авторы: Creary, Lisa E., Ulug, Pinar, Menzel, Stephan, McKenzie, Colin A., Hanchard, Neil A., Taylor, Veronica, Farrall, Martin, Forrester, Terrence E., Thein, Swee Lay
Формат: Artigo
Язык:Inglês
Опубликовано: Public Library of Science 2009
Предметы:
Research Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC2621086/
https://ncbi.nlm.nih.gov/pubmed/19148297
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0004218
Метки: Добавить метку
Нет меток, Требуется 1-ая метка записи!

Схожие документы