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Genetic modifiers of HbF and Response to Hydroxyurea in Sickle Cell Disease
Fetal hemoglobin (HbF) levels are generally inversely proportional to severity of sickle cell disease (SCD) for given sickle phenotypes. Molecular regulation of HbF occurs through complex interactions cis and trans to the beta globin gene locus. Novel insights made through population-based genetic e...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3006002/ https://ncbi.nlm.nih.gov/pubmed/20830771 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pbc.22754 |
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