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Fetal Hemoglobin in Sickle Hemoglobinopathies: High HbF Genotypes and Phenotypes

Fetal hemoglobin (HbF) usually consists of 4 to 10% of total hemoglobin in adults of African descent with sickle cell anemia. Rarely, their HbF levels reach more than 30%. High HbF levels are sometimes a result of β-globin gene deletions or point mutations in the promoters of the HbF genes. Collecti...

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Dades bibliogràfiques
Publicat a:J Clin Med
Autor principal: Steinberg, Martin H.
Format: Artigo
Idioma:Inglês
Publicat: MDPI 2020
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7700170/
https://ncbi.nlm.nih.gov/pubmed/33238542
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/jcm9113782
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