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Fetal Hemoglobin in Sickle Hemoglobinopathies: High HbF Genotypes and Phenotypes
Fetal hemoglobin (HbF) usually consists of 4 to 10% of total hemoglobin in adults of African descent with sickle cell anemia. Rarely, their HbF levels reach more than 30%. High HbF levels are sometimes a result of β-globin gene deletions or point mutations in the promoters of the HbF genes. Collecti...
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| Publicado no: | J Clin Med |
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| Autor principal: | |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
MDPI
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7700170/ https://ncbi.nlm.nih.gov/pubmed/33238542 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/jcm9113782 |
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