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Fetal hemoglobin in sickle cell anemia

Fetal hemoglobin (HbF) can blunt the pathophysiology, temper the clinical course, and offer prospects for curative therapy of sickle cell disease. This review focuses on (1) HbF quantitative trait loci and the geography of β-globin gene haplotypes, especially those found in the Middle East; (2) how...

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Détails bibliographiques
Publié dans:Blood
Auteur principal: Steinberg, Martin H.
Format: Artigo
Langue:Inglês
Publié: American Society of Hematology 2020
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7685210/
https://ncbi.nlm.nih.gov/pubmed/32808012
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood.2020007645
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