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Fetal hemoglobin in sickle cell anemia
Fetal hemoglobin (HbF) is the major genetic modulator of the hematologic and clinical features of sickle cell disease, an effect mediated by its exclusion from the sickle hemoglobin polymer. Fetal hemoglobin genes are genetically regulated, and the level of HbF and its distribution among sickle eryt...
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| Main Authors: | , , , , , , , |
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| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
American Society of Hematology
2011
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3139383/ https://ncbi.nlm.nih.gov/pubmed/21490337 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2011-03-325258 |
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