Fetal hemoglobin in sickle cell anemia

Fetal hemoglobin (HbF) is the major genetic modulator of the hematologic and clinical features of sickle cell disease, an effect mediated by its exclusion from the sickle hemoglobin polymer. Fetal hemoglobin genes are genetically regulated, and the level of HbF and its distribution among sickle eryt...

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Bibliographic Details
Main Authors: Akinsheye, Idowu, Alsultan, Abdulrahman, Solovieff, Nadia, Ngo, Duyen, Baldwin, Clinton T., Sebastiani, Paola, Chui, David H. K., Steinberg, Martin H.
Format: Artigo
Language:Inglês
Published: American Society of Hematology 2011
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Review Articles
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3139383/
https://ncbi.nlm.nih.gov/pubmed/21490337
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2011-03-325258
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