Fetal Hemoglobin in Sickle Cell Anemia: Genetic Studies of the Arab-Indian Haplotype

Sickle cell anemia is common in the Middle East and India where the HbS gene is sometimes associated with the Arab-Indian (AI) β-globin gene (HBB) cluster haplotype. In this haplotype of sickle cell anemia, fetal hemoglobin (HbF) levels are 3-4 fold higher than those found in patients with HbS haplo...

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Hlavní autoři: Ngo, Duyen, Bae, Harold, Steinberg, Martin H., Sebastiani, Paola, Solovieff, Nadia, Baldwin, Clinton T., Melista, Efthymia, Safaya, Surinder, Farrar, Lindsay A., Suliman, Ahmed M., Albuali, Waleed H., Al Bagshi, Muneer H., Akinsheye, Idowu, Gallagher, Patrick, Luo, Hong-yuan, Chui, David H.K., Farrell, John J., Al-Ali, Amein K., Alsultan, Abdulrahman
Médium: Artigo
Jazyk:Inglês
Vydáno: 2013
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3647015/
https://ncbi.nlm.nih.gov/pubmed/23465615
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bcmd.2012.12.005
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