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Structural and Biochemical Studies of TIGAR (TP53-induced Glycolysis and Apoptosis Regulator)
Activation of the p53 tumor suppressor by cellular stress leads to variable responses ranging from growth inhibition to apoptosis. TIGAR is a novel p53-inducible gene that inhibits glycolysis by reducing cellular levels of fructose-2,6-bisphosphate, an activator of glycolysis and inhibitor of glucon...
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| Autors principals: | , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
American Society for Biochemistry and Molecular Biology
2009
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2615519/ https://ncbi.nlm.nih.gov/pubmed/19015259 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M807821200 |
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