TP53-inducible Glycolysis and Apoptosis Regulator (TIGAR) Metabolically Reprograms Carcinoma and Stromal Cells in Breast Cancer

A subgroup of breast cancers has several metabolic compartments. The mechanisms by which metabolic compartmentalization develop in tumors are poorly characterized. TP53 inducible glycolysis and apoptosis regulator (TIGAR) is a bisphosphatase that reduces glycolysis and is highly expressed in carcino...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Ko, Ying-Hui, Domingo-Vidal, Marina, Roche, Megan, Lin, Zhao, Whitaker-Menezes, Diana, Seifert, Erin, Capparelli, Claudia, Tuluc, Madalina, Birbe, Ruth C., Tassone, Patrick, Curry, Joseph M., Navarro-Sabaté, Àurea, Manzano, Anna, Bartrons, Ramon, Caro, Jaime, Martinez-Outschoorn, Ubaldo
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2016
Assuntos:
Bioenergetics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5159492/
https://ncbi.nlm.nih.gov/pubmed/27803158
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M116.740209
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