Cigarette Smoke Induces Metabolic Reprogramming of the Tumor Stroma in Head and Neck Squamous Cell Carcinoma

Head and neck squamous cell carcinoma (HNSCC) is comprised of metabolically linked distinct compartments. Cancer-associated fibroblasts (CAFs) and non-proliferative carcinoma cells display a glycolytic metabolism, whilst proliferative carcinoma cells rely on mitochondrial oxidative metabolism fueled...

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Detalhes bibliográficos
Publicado no:Mol Cancer Res
Main Authors: Domingo-Vidal, Marina, Whitaker-Menezes, Diana, Martos-Rus, Cristina, Tassone, Patrick, Snyder, Christopher M., Tuluc, Madalina, Philp, Nancy, Curry, Joseph, Martinez-Outschoorn, Ubaldo
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6726526/
https://ncbi.nlm.nih.gov/pubmed/31239287
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1541-7786.MCR-18-1191
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