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UBXD7 binds multiple ubiquitin ligases and implicates p97 in HIF1alpha turnover
The ATPase p97/Cdc48 promotes degradation of ubiquitin-conjugated proteins and its ability to bind substrates is mediated by cofactors containing ubiquitin-binding domains, such as NPL4/UFD1 or the yeast UBX domain protein Ubx2. Here, we employed 'network proteomics' to show that p97 assem...
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| Auteurs principaux: | , , , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2008
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2614663/ https://ncbi.nlm.nih.gov/pubmed/18775313 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2008.06.048 |
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