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Cdc48/p97 mediates UV-dependent turnover of RNA Pol II

Cdc48/p97 is an essential ATPase whose role in targeting substrates to the ubiquitin-proteasome system (UPS) remains unclear. Existing models posit that Cdc48 acts upstream of UPS receptors. To address this hypothesis, we examined the association of ubiquitin (Ub) conjugates with 26S proteasomes. Un...

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Autors principals: Verma, Rati, Oania, Robert, Fang, Ruihua, Smith, Geoffrey T., Deshaies, Raymond J.
Format: Artigo
Idioma:Inglês
Publicat: 2011
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3063307/
https://ncbi.nlm.nih.gov/pubmed/21211725
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2010.12.017
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