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Cdc48/p97 mediates UV-dependent turnover of RNA Pol II

Cdc48/p97 is an essential ATPase whose role in targeting substrates to the ubiquitin-proteasome system (UPS) remains unclear. Existing models posit that Cdc48 acts upstream of UPS receptors. To address this hypothesis, we examined the association of ubiquitin (Ub) conjugates with 26S proteasomes. Un...

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Bibliografiske detaljer
Main Authors: Verma, Rati, Oania, Robert, Fang, Ruihua, Smith, Geoffrey T., Deshaies, Raymond J.
Format: Artigo
Sprog:Inglês
Udgivet: 2011
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3063307/
https://ncbi.nlm.nih.gov/pubmed/21211725
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2010.12.017
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