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NEDD8 links Cullin–Ring ubiquitin Ligase function to the p97 pathway
The AAA ATPase p97 and its UBA-UBX cofactors are thought to extract ubiquitinated proteins from membranes or protein complexes as a prelude to their degradation. However, ubiquitinated targets have not yet been identified for many cofactors, leaving their biological function unclear. Previous analys...
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| Główni autorzy: | , , , , |
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| Format: | Artigo |
| Język: | Inglês |
| Wydane: |
2012
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| Hasła przedmiotowe: | |
| Dostęp online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3348432/ https://ncbi.nlm.nih.gov/pubmed/22466964 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nsmb.2269 |
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