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Inhibition of erythroblast growth and fetal hemoglobin production by ribofuranose-substituted adenosine derivatives
In vivo, inhibition of fetal hemoglobin (HbF) expression in humans around the time of birth causes the clinical manifestation of sickle cell and beta-thalassemia syndromes. Inhibition of HbF among cultured cells was recently described by the adenosine derivative molecule named SQ22536. Here, a prima...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2613185/ https://ncbi.nlm.nih.gov/pubmed/18586086 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbadis.2008.05.004 |
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