Inhibition of erythroblast growth and fetal hemoglobin production by ribofuranose-substituted adenosine derivatives

In vivo, inhibition of fetal hemoglobin (HbF) expression in humans around the time of birth causes the clinical manifestation of sickle cell and beta-thalassemia syndromes. Inhibition of HbF among cultured cells was recently described by the adenosine derivative molecule named SQ22536. Here, a prima...

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Detaylı Bibliyografya
Asıl Yazarlar: Bhanu, Natarajan V., Lee, Y. Terry, Oneal, Patricia A., Gantt, Nicole M., Aerbajinai, Wulin, Noel, Pierre, Thomas, Craig J., Miller, Jeffery L.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2008
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC2613185/
https://ncbi.nlm.nih.gov/pubmed/18586086
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbadis.2008.05.004
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