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Fetal hemoglobin silencing in humans

Interruption of the normal fetal-to-adult transition of hemoglobin expression should largely ameliorate sickle cell and beta-thalassemia syndromes. Achievement of this clinical goal requires a robust understanding of gamma-globin gene and protein silencing during human development. For this purpose,...

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Detalhes bibliográficos
Main Authors: Oneal, Patricia A., Gantt, Nicole M., Schwartz, Joseph D., Bhanu, Natarajan V., Lee, Y. Terry, Moroney, John W., Reed, Christopher H., Schechter, Alan N., Luban, Naomi L. C., Miller, Jeffery L.
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society of Hematology 2006
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1895549/
https://ncbi.nlm.nih.gov/pubmed/16735596
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2006-04-015859
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