Fetal hemoglobin silencing in humans

Interruption of the normal fetal-to-adult transition of hemoglobin expression should largely ameliorate sickle cell and beta-thalassemia syndromes. Achievement of this clinical goal requires a robust understanding of gamma-globin gene and protein silencing during human development. For this purpose,...

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Main Authors: Oneal, Patricia A., Gantt, Nicole M., Schwartz, Joseph D., Bhanu, Natarajan V., Lee, Y. Terry, Moroney, John W., Reed, Christopher H., Schechter, Alan N., Luban, Naomi L. C., Miller, Jeffery L.
Format: Artigo
Jezik:Inglês
Izdano: The American Society of Hematology 2006
Teme:
Red Cells
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC1895549/
https://ncbi.nlm.nih.gov/pubmed/16735596
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2006-04-015859
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