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Cytokine-mediated increases in fetal hemoglobin are associated with globin gene histone modification and transcription factor reprogramming

Therapeutic regulation of globin genes is a primary goal of translational research aimed toward hemoglobinopathies. Signal transduction was used to identify chromatin modifications and transcription factor expression patterns that are associated with globin gene regulation. Histone modification and...

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Detalhes bibliográficos
Main Authors: Sripichai, Orapan, Kiefer, Christine M., Bhanu, Natarajan V., Tanno, Toshihiko, Noh, Seung-Jae, Goh, Sung-Ho, Russell, J. Eric, Rognerud, Cheryl L., Ou, Ching-Nan, Oneal, Patricia A., Meier, Emily R., Gantt, Nicole M., Byrnes, Colleen, Lee, Y. Terry, Dean, Ann, Miller, Jeffery L.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2745848/
https://ncbi.nlm.nih.gov/pubmed/19597182
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2009-05-219386
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