Cytokine-mediated increases in fetal hemoglobin are associated with globin gene histone modification and transcription factor reprogramming

Therapeutic regulation of globin genes is a primary goal of translational research aimed toward hemoglobinopathies. Signal transduction was used to identify chromatin modifications and transcription factor expression patterns that are associated with globin gene regulation. Histone modification and...

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Bibliographic Details
Main Authors: Sripichai, Orapan, Kiefer, Christine M., Bhanu, Natarajan V., Tanno, Toshihiko, Noh, Seung-Jae, Goh, Sung-Ho, Russell, J. Eric, Rognerud, Cheryl L., Ou, Ching-Nan, Oneal, Patricia A., Meier, Emily R., Gantt, Nicole M., Byrnes, Colleen, Lee, Y. Terry, Dean, Ann, Miller, Jeffery L.
Format: Artigo
Language:Inglês
Published: American Society of Hematology 2009
Subjects:
Red Cells, Iron, and Erythropoiesis
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2745848/
https://ncbi.nlm.nih.gov/pubmed/19597182
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2009-05-219386
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