Cytokine-mediated increases in fetal hemoglobin are associated with globin gene histone modification and transcription factor reprogramming

Therapeutic regulation of globin genes is a primary goal of translational research aimed toward hemoglobinopathies. Signal transduction was used to identify chromatin modifications and transcription factor expression patterns that are associated with globin gene regulation. Histone modification and...

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Hlavní autoři: Sripichai, Orapan, Kiefer, Christine M., Bhanu, Natarajan V., Tanno, Toshihiko, Noh, Seung-Jae, Goh, Sung-Ho, Russell, J. Eric, Rognerud, Cheryl L., Ou, Ching-Nan, Oneal, Patricia A., Meier, Emily R., Gantt, Nicole M., Byrnes, Colleen, Lee, Y. Terry, Dean, Ann, Miller, Jeffery L.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society of Hematology 2009
Témata:
Red Cells, Iron, and Erythropoiesis
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2745848/
https://ncbi.nlm.nih.gov/pubmed/19597182
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2009-05-219386
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