Restoration of Hepatic Glucokinase Expression Corrects Hepatic Glucose Flux and Normalizes Plasma Glucose in Zucker Diabetic Fatty Rats

OBJECTIVE—We examined in 20-week-old Zucker diabetic fatty (ZDF) rats whether restoration of hepatic glucokinase (GK) expression would alter hepatic glucose flux and improve hyperglycemia. RESEARCH DESIGN AND METHODS—ZDF rats were treated at various doses with an adenovirus that directs the expressi...

Celý popis

Uloženo v:
Podrobná bibliografie
Hlavní autoři: Torres, Tracy P., Catlin, ReEtta L., Chan, Robert, Fujimoto, Yuka, Sasaki, Noriyasu, Printz, Richard L., Newgard, Christopher B., Shiota, Masakazu
Médium: Artigo
Jazyk:Inglês
Vydáno: American Diabetes Association 2009
Témata:
Metabolism
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2606896/
https://ncbi.nlm.nih.gov/pubmed/18952838
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db08-1119
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky