טוען...
Efficient gene targeting in Drosophila by direct embryo injection with zinc-finger nucleases
We report very high gene targeting frequencies in Drosophila by direct embryo injection of mRNAs encoding specific zinc-finger nucleases (ZFNs). Both local mutagenesis via nonhomologous end joining (NHEJ) and targeted gene replacement via homologous recombination (HR) have been achieved in up to 10%...
שמור ב:
| Main Authors: | , , , , , , |
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| פורמט: | Artigo |
| שפה: | Inglês |
| יצא לאור: |
National Academy of Sciences
2008
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| נושאים: | |
| גישה מקוונת: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2604940/ https://ncbi.nlm.nih.gov/pubmed/19064913 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0810475105 |
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