Structure-Activity Relationships of Bifunctional Cyclic Disulfide Peptides Based on Overlapping Pharmacophores at Opioid and Cholecystokinin Receptors

Prolonged opioid exposure increases the expression of cholecystokinin (CCK) and its receptors in the central nervous system, where CCK may attenuate the antinociceptive effects of opioids. The complex interactions between opioid and CCK may play a role in the development of opioid tolerance. We desi...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Päätekijät: Agnes, Richard S., Ying, Jinfa, Kövér, Katalin E., Lee, Yeon Sun, Davis, Peg, Ma, Shou-wu, Badghisi, Hamid, Porreca, Frank, Lai, Josephine, Hruby, Victor J.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2008
Aiheet:
Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC2601673/
https://ncbi.nlm.nih.gov/pubmed/18502541
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.peptides.2008.03.022
Tagit: Lisää tagi
Ei tageja, Lisää ensimmäinen tagi!

Samankaltaisia teoksia