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Synthesis of constrained analogues of cholecystokinin/opioid chimeric peptides

In our ongoing research on the synthesis of constrained analogues of CCK/opioid chimeric peptides, a bicyclic dipeptide mimetic for Nle-Asp was designed and synthesized. Starting from β-allyl substituted aspartic acids, the terminal double bond was oxidized resulting in spontaneous cyclization to fo...

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Detalhes bibliográficos
Main Authors: Ndungu, John M., Cain, James P., Davis, Peg, Ma, Shou-W., Vanderah, Todd W., Lai, Josephine, Porreca, Frank, Hruby, Victor J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1761685/
https://ncbi.nlm.nih.gov/pubmed/17203138
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tetlet.2006.01.096
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