Structure-Activity Relationships of Bifunctional Cyclic Disulfide Peptides Based on Overlapping Pharmacophores at Opioid and Cholecystokinin Receptors

Prolonged opioid exposure increases the expression of cholecystokinin (CCK) and its receptors in the central nervous system, where CCK may attenuate the antinociceptive effects of opioids. The complex interactions between opioid and CCK may play a role in the development of opioid tolerance. We desi...

Descripció completa

Guardat en:
Dades bibliogràfiques
Autors principals: Agnes, Richard S., Ying, Jinfa, Kövér, Katalin E., Lee, Yeon Sun, Davis, Peg, Ma, Shou-wu, Badghisi, Hamid, Porreca, Frank, Lai, Josephine, Hruby, Victor J.
Format: Artigo
Idioma:Inglês
Publicat: 2008
Matèries:
Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2601673/
https://ncbi.nlm.nih.gov/pubmed/18502541
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.peptides.2008.03.022
Etiquetes: Afegir etiqueta
Sense etiquetes, Sigues el primer a etiquetar aquest registre!

Ítems similars