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Inhibition of HLA-DQ2 Mediated Antigen Presentation by Analogues of a High Affinity 33-Residue Peptide from α2-Gliadin

Human leukocyte antigen DQ2 is a class II major histocompatibility complex protein that plays a critical role in the pathogenesis of Celiac Sprue by binding to epitopes derived from dietary gluten and triggering the inflammatory response of disease-specific T cells. Inhibition of DQ2 mediated antige...

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Detalles Bibliográficos
Main Authors: Xia, Jiang, Siegel, Matthew, Bergseng, Elin, Sollid, Ludvig M., Khosla, Chaitan
Formato: Artigo
Idioma:Inglês
Publicado: 2006
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2597451/
https://ncbi.nlm.nih.gov/pubmed/16464085
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja056423o
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