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Inhibition of HLA-DQ2 Mediated Antigen Presentation by Analogues of a High Affinity 33-Residue Peptide from α2-Gliadin
Human leukocyte antigen DQ2 is a class II major histocompatibility complex protein that plays a critical role in the pathogenesis of Celiac Sprue by binding to epitopes derived from dietary gluten and triggering the inflammatory response of disease-specific T cells. Inhibition of DQ2 mediated antige...
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| Главные авторы: | , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2006
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2597451/ https://ncbi.nlm.nih.gov/pubmed/16464085 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja056423o |
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