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Telomerase-dependent and independent chromosome healing in mouse embryonic stem cells

Telomeres play an important role in protecting the ends of chromosomes and preventing chromosome fusion. We have previously demonstrated that double-strand breaks near telomeres in mammalian cells result in either the addition of a new telomere at the site of the break, termed chromosome healing, or...

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Detalhes bibliográficos
Main Authors: Gao, Qing, Reynolds, Gloria E., Wilcox, Andrew, Miller, Douglas, Cheung, Peggie, Artandi, Steven E., Murnane, John P.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2597172/
https://ncbi.nlm.nih.gov/pubmed/18502190
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.dnarep.2008.04.004
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