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Telomerase-dependent and independent chromosome healing in mouse embryonic stem cells

Telomeres play an important role in protecting the ends of chromosomes and preventing chromosome fusion. We have previously demonstrated that double-strand breaks near telomeres in mammalian cells result in either the addition of a new telomere at the site of the break, termed chromosome healing, or...

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Bibliografiske detaljer
Main Authors: Gao, Qing, Reynolds, Gloria E., Wilcox, Andrew, Miller, Douglas, Cheung, Peggie, Artandi, Steven E., Murnane, John P.
Format: Artigo
Sprog:Inglês
Udgivet: 2008
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2597172/
https://ncbi.nlm.nih.gov/pubmed/18502190
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.dnarep.2008.04.004
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